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Common Signature of Diabetes and Oxidative stress



Network: H. sapiens miRNA-regulated interactome (H. sapiens)
The network was constructed using protein-protein interactions from BioGRID version 2.42 and documented miRNA targets from TarBase.

Experiment: Comparison between the networks for diabetes and oxidative stress revealed many common genes which may be the first and most obvious evidence for common molecular mechanisms. Additionally, diabetes and oxidative stress genes may act in a cooperative manner at the protein level or could be co-regulated by the same miRNA molecules.